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Pixantrone (dimaleate) Catalog No.:M9764-10 Effect of Small Molecules Modulating

SKU: 9378446662

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Description

Effect of Small Molecules Modulating Androgen Receptor (SARMs) in Human Prostate Cancer Models

Chemical Name: N-(trans-3-[5-[(1R)-1-hydroxyethyl]-1

Epub 2012 Jul 23

The short-term suppression of cell functions is followed by a significant temporary increase of specific growth rate and of specific production rate

Pixantrone (dimaleate) Catalog No.:M9764-10 Effect of Small Molecules ModulatingPixantrone is a synthetic, noncardiotoxic aza anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Pixantrone is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non Hodgkin lymphoma (aNHL). Product information CAS Number:

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