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Smiles: O=C1CC(OC2=CC=CC=C21)C1C=CC=CC=1
and oral bioavailability of 32%
Smiles: CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](CC1C=CC=CC=1)C1=NC=CS1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)CCCCCN1C(=O)C(CC1=O)SC[C@H](N)C(O)=O)C(C)C
95(4):270-82
BI-3802 PyP4 tosylate Smiles: O=C1CC(OC2=CC=CC=C21)C1C=CC=CC=1BI 3802 is a highly potent BCL6 degrader and inhibits the Bric brac (BTB) domain of BCL6 with an IC50 of 3 nM. BI 3802 induces the polymerization of BCL6 and promotes BCL6 degration depended on E3 ligase SIAH1. BI 3802 has antitumor activity. Product information CAS Number: 2166387 65 9 Molecular Weight: 484. 98 Formula: C24H29ClN6O3 Chemical Name: 2 {[6 ({5 chloro 2 [(3R,5S) 3,5 dimethylpiperidin 1 yl]pyrimidin 4 yl}amino) 1 methyl 2 oxo 1,2
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