Bictegravir 51322 Bis-propargyl-PEG8 (compound 16e) is a

Bis-propargyl-PEG8 (compound 16e) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs

Further assessment in both acute and chronic safety pharmacology and toxicology studies demonstrated a clean profile up to high plasma levels

Molecular Weight: 557

Formula: C10H12N4O3

Bictegravir 51322 Bis-propargyl-PEG8 (compound 16e) is aBictegravir (GS 9883) is a potent inhibitor of HIV 1 integrase with an IC50 of 7. 5 nM. Product information CAS Number: 1611493 60 7 Molecular Weight: 449. 38 Formula: C21H18F3N3O5 Chemical Name: (1S,11R,13R) 5 hydroxy 3,6 dioxo N [(2,4,6 trifluorophenyl)methyl] 12 oxa 2,9 diazatetracyclo[11. 2. 1. 0,. 0,]hexadeca 4,7 diene 7 carboxamide Smiles: OC1=C2C(=O)N3[C@@H](CN2C=C(C(=O)NCC2C(F)=CC(F)=CC=2F)C1=O)O[C@H]1C[C@@H]3CC1 InChiKey: SOLUWJRYJLAZCX