Asenapine Hydrochloride - CAS# 1412458-61-7 uorowillardiine hydrochloride 25 µM) inhibits LPS-induced increases

25 µM) inhibits LPS-induced increases in inducible nitric oxide synthase (iNOS) and COX-2 levels

8-dimethyl-5-(4-methylphenyl)-7

2013 Oct 22

BSJ-03-123 is a phthalimide-based degrader that exploits protein-interface determinants to achieve proteome-wide selectivity for the degradation of cyclin-dependent kinase 6 (CDK6)

Asenapine Hydrochloride - CAS# 1412458-61-7 uorowillardiine hydrochloride 25 µM) inhibits LPS-induced increasesAsenapine, also known as Org 5222 and HSDB 8061, shows high affinity (pKi) for numerous receptors, including the serotonin 5 HT1A (8. 6), 5 HT1B (8. 4), 5 HT2A (10. 2), 5 HT2B (9. 8), 5 HT2C (10. 5), 5 HT5A (8. 8), 5 HT6 (9. 5), and 5 HT7 (9. 9) receptors, the adrenergic 1 (8. 9), 2A (8. 9), 2B (9. 5), and 2C (8. 9) receptors, the dopamine D1 (8. 9), D2 (8. 9), D3 (9. 4), and D4 (9. 0) receptors, and the histamine H1 (9. 0) and H2 (8. 2) receptors.