GPi 688 3234 4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide

4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide

2-c]pyridine inhibitors of mitotic kinase monopolar spindle 1 (MPS1)

Smiles: CN(C)C1=CC=C(CN2C=NC3CN([C@@H](CC2=3)C(O)=O)C(=O)C(C2C=CC=CC=2)C2C=CC=CC=2)C=C1C

exhibits potent antitumor activity against a human lung cancer cell line and its SN-38-resistant variant

GPi 688 3234 4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamideProduct information CAS Number: 918902 32 6 Molecular Weight: 419. 88 Formula: C19H18ClN3O4S Chemical Name: 2 chloro N {1 [(2R) 2,3 dihydroxypropyl] 2 oxo 1,2,3,4 tetrahydroquinolin 3 yl} 6H thieno[2,3 b]pyrrole 5 carboxamide Smiles: O[C@H](CN1C(=O)C(CC2=CC=CC=C12)NC(=O)C1=CC2C=C(Cl)SC=2N1)CO InChiKey: UICNBXVDHCBKCE PUODRLBUSA N InChi: InChI=1S C19H18ClN3O4S c20 16 7 11 6 13(22 18(11)28 16)17(26)21 14 5 10 3 1 2 4 15(10)23(19(14)27)8 12(25)9 24 h1