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JAK3-IN-1(Compound 9) most potently inhibits JAK3 and identified fms-related tyrosine kinase 3 (FLT3) and several tyrosine protein kinase (TEC)-family kinases as being potential off-targets
Nilsson UJ
5S)-5-[di(²H₃)methylcarbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3
InChiKey: DSEIKQVUTKGLGT-UHFFFAOYSA-N
Narirutin 15731 JAK3-IN-1(Compound 9) most potently inhibitsNarirutin, one of the active constituents isolated from Citrus unshiu, has antioxidant and anti inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti tubercular potency. Product information CAS Number: 14259 46 2 Molecular Weight: 580. 53 Formula: C27H32O14 Chemical Name: (2S) 5 hydroxy 2 (4 hydroxyphenyl) 7 {[(2S,3R,4S,5S,6R) 3,4,5 trihydroxy 6 ({[(2R,3R,4R,5R,6S) 3,4,5 trihydroxy 6 methyloxan 2 yl]oxy}methyl)oxan 2 yl]oxy} 3,4
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