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Chemical Name: 11-hydroxy-8-methoxy-4-methyl-10-{[(2S
Formula: C26H26O4
InChi: InChI=1S/C5H8O3/c1-2-3-4(6)5(7)8/h2-3H2
CAS Number: 1839519-57-1
GNE-616 emsirolimus Chemical Name: 11-hydroxy-8-methoxy-4-methyl-10-{[(2SGNE 616 is a highly potent, metabolically stable, orally bioavailable, and subtype selective Nav1. 7 inhibitor (Ki of 0. 79 nM and Kd of 0. 38 nM for hNav1. 7) for the treatment of chronic pain. GNE 616 shows >1000 nM Kd and >2500 fold selectivity over hNav1. 1, hNav1. 3, hNav1. 4, and hNav1. 5. Selectivity over hNav1. 2 and hNav1. 6 is more modest at 31 and 73 fold, respectively. Product information CAS Number: 2349371 81 7 Molecular Weight: 537. 53
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