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25-Dihydroxyvitamin D3 ((24S)-24
Formula: C5H3N5O2S3
and decreases DNMT1 and UHRF1 mRNA and protein expression
InChi: InChI=1S/C30H32F6N4O2/c1-28(2
PF-CBP1 hydrochloride Size:2mg solid 25-Dihydroxyvitamin D3 ((24S)-24PF CBP1 hydrochloride is a highly selective inhibitor of the CREB binding protein bromodomain (CBP BRD). PF CBP1 inhibits CREBBP and EP300 bromodomains with IC50 of 125 nM and 363 nM respectively. PF CBP1 hydrochloride reduces LPS induced inflammatory cytokines expression (IL 1, IL 6 and IFN ) in primary macrophages. PF CBP1 hydrochloride also downregulates RGS4 expression cortical neurons and can be used for the research of neurological disorders,
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