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Lichtenthaler SF
shows 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases
133053-19-7
Formula: C18H28ClN3O3
Netarsudil Mesylate - CAS# 1422144-42-0 Catalog No.:M6862-10 Lichtenthaler SFNetarsudil Mesylate, CAS No. 1422144 42 0, also known as AR 11324, is a Rho associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and or reducing intraocular pressure. Netarsudil Increases Outflow Facility in Human Eyes Through Multiple Mechanisms. Netarsudil inhibited kinases ROCK1 and ROCK2 with a Ki of 1 nM each, disrupted actin stress fibers and focal adhesions in TM cells with IC50s of 79 and 16 nM,
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