GGTI-2154 - CAS# 251577-10-3 Size:Contact [email protected] for quotation Smiles: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)C1=C(O)C(C(=O)C2C=CC(O)=CC=2)=C(O)C=C1O

Smiles: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)C1=C(O)C(C(=O)C2C=CC(O)=CC=2)=C(O)C=C1O

InChi: InChI=1S/C18H14N4/c1-12-5-4-8-17(21-12)18-15(11-20-22-18)13-9-10-19-16-7-3-2-6-14(13)16/h2-11H

or by MTT assay (IC50 of 45 µM)

Formula: C28H30INO

GGTI-2154 - CAS# 251577-10-3 Size:Contact [email protected] for quotation Smiles: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)C1=C(O)C(C(=O)C2C=CC(O)=CC=2)=C(O)C=C1OGGTI 2154 is a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I), with an IC50 of 21 nM. GGTI 2154 shows more than 200 fold selectivity for GGTase I over FTase (IC50=5600 nM). GGTI 2154 can be used for the research of cancer. Product information CAS Number: 251577 10 3 Molecular Weight: 420. 50 Formula: C24H28N4O3 Chemical Name: 2 [(4 {[(1H imidazol 5 yl)methyl]amino} 2' methyl [1,1' biphenyl] 2 yl)formamido] 4 methylpentanoic