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RepSox is able to successfully replace Sox2 in reprogramming by inhibiting transforming growth factor-β (Tgf-β) signaling
Chemical Name: 4-((((4-methoxyphenyl)sulfonyl)oxy)imino)-2
N-benzoylated phenoxazines and phenothiazines: synthesis
It activates human TRPA1 via photochemical reactions with redox-sensitive cysteine residues (EC50 ~2 µM)
Rosuvastatin Calcium 60107 RepSox is able to successfullyRosuvastatin Calcium (Rosuvastatin hemicalcium) is a competitive HMG CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks human ether a go go related gene (hERG) current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock
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