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3R)-2-(2-chloroacetyl)-1-(4-(methoxycarbonyl)phenyl)-2
InChiKey: LIOLIMKSCNQPLV-UHFFFAOYSA-N
(2010) Mol Cancer Ther
Mäkinen P
CERC-501 - CAS# 1174130-61-0 60224 3R)-2-(2-chloroacetyl)-1-(4-(methoxycarbonyl)phenyl)-2CERC 501, also known as JNJ 67953964, LY 2456302 and Aticaprant, CAS No. 1174130 61 0, is a potent, selective, short acting antagonist of the opioid receptor (KOR) (Ki = 0. 81 nM vs. 24. 0 nM and 155 nM for the opioid receptor (MOR) and opioid receptor (DOR). Aticaprant is under development for the treatment of major depressive disorder and substance use disorders including alcoholism, nicotine addiction, and illicit drug dependence. Aticaprant has
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