N-Desethyl Sunitinib hydrochloride Catalog No.:M34737-C GYKI 53655 hydrochloride (4 mg/kg)

GYKI 53655 hydrochloride (4 mg/kg) is found to have a short-lasting depressant effect on neuronal responses to iontophoreticα-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)

InChiKey: LVRFTAZAXQPQHI-RXMQYKEDSA-N

The concentrations of trans-ACPD required to evoke half-maximal stimulation (EC50 value) is 51 μM

CAS Number: 1034297-58-9

N-Desethyl Sunitinib hydrochloride Catalog No.:M34737-C GYKI 53655 hydrochloride (4 mg/kg)N Desethyl Sunitinib (SU 12662) (hydrochloride) is a metabolite of sunitinib. Sunitinib is a potent, ATP competitive VEGFR, PDGFR and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR 1, 2, 3, PDGFR and KIT, respectively. Product information Molecular Weight: 406. 88 Formula: C20H24ClFN4O2 Chemical Name: N [2 (ethylamino)ethyl] 5 {[(3Z) 5 fluoro 2 oxo 2,3 dihydro 1H indol 3 ylidene]methyl} 2,4 dimethyl 1H pyrrole 3 carboxamide