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13-trihydroxy-13-[(2R
anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1)
3-H)propan-2-yl]pyrimidin-5-yl]-3
These results indicate that inhibition of BMP signaling may successfully target both the tumor and the surrounding microenvironment to reduce tumor burden and metastasis
JC-171 IN 3 13-trihydroxy-13-[(2RJC 171 is a selective NLRP3 inflammasome inhibitor, with an IC50 of 8. 45 M for inhibiting LPS ATP induced interleukin 1 (IL 1) release from J774A. 1 macrophages. Product information CAS Number: 2112809 98 8 Molecular Weight: 384. 83 Formula: C16H17ClN2O5S Chemical Name: 5 chloro N {2 [4 (hydroxysulfamoyl)phenyl]ethyl} 2 methoxybenzamide Smiles: COC1=CC=C(Cl)C=C1C(=O)NCCC1C=CC(=CC=1)S(=O)(=O)NO InChiKey: KQRQPMUPYDOTCA UHFFFAOYSA N InChi: InChI=1S
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