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Camptothecin peptide conjugates
GBT440 increases haemoglobin oxygen affinity
5-70 mg/kg
7 μg•hour/mL in HT1080 fibrosarcoma model
Gossypol-acetic acid - CAS# 12542-36-8 Catalog No.:M11332-10 Camptothecin peptide conjugatesGossypol is an orally active polyphenolic aldehyde with potential antineoplastic activity. Derived primarily from unrefined cottonseed oil, gossypol induces cell cycle arrest at the G0 G1 phase, thereby inhibiting DNA replication and inducing apoptosis. This agent also inhibits cell signaling enzymes, resulting in inhibition of cell growth, and may act as a male contraceptive. Product information CAS Number: 12542 36 8 Molecular Weight: 578. 61
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