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Four weeks of treatment with BTZ043 reduces the bacterial burden in the lungs and spleens by 1 and 2 logs
and p70S6K in a dose-dependent manner
embryonic kidney cyst model
4)5)12-21(20)36-23/h7-8
Bicyclol ioguanine Four weeks of treatment withBicyclol, also known as SY 801, is a hepatoprotective agent. Bicyclol upregulates transcription factor Nrf2, HO 1 expression and protects rat brains against focal ischemia. Bicyclol induces cell cycle arrest and autophagy in HepG2 human hepatocellular carcinoma cells through the PI3K AKT and Ras Raf MEK ERK pathways. Bicyclol attenuates tetracycline induced fatty liver associated with inhibition of hepatic ER stress and apoptosis in mice. Bicyclol
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