IMR-1A hoquine phosphate InChi: InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H

InChi: InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H

is a potent and selective allosteric protein arginine methyltransferase 3 (PRMT3) inhibitor with IC50 ~ 230 nM

and colon cancer

GW9508 is shown to be at least 100-fold selective against 220 other GPCRs

IMR-1A hoquine phosphate InChi: InChI=1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6HIMR 1A, a acid metabolite of IMR 1, is a Notch inhibitor with an IC50 of 0. 5 M. IMR 1A has a 50 fold increase in potency with respect to IMR 1. IMR 1 can metabolize in vivo to IMR 1A. Product information CAS Number: 331862 41 0 Molecular Weight: 325. 36 Formula: C13H11NO5S2 Chemical Name: 2 (2 methoxy 4 {[(5E) 4 oxo 2 sulfanylidene 1, 3 thiazolidin 5 ylidene]methyl}phenoxy)acetic acid Smiles: COC1=CC(=CC=C1OCC(O)=O) C=C1 SC(=S)NC 1=O InChiKey: