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Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1
Smiles: CCCN1CCN(CC1)C1=CC=C(C=C1)C(=O)NC1(CCCCC1)C(=O)NCC#N
after oral administration
InChi: InChI=1S/C55H65N5O9S2/c1-7-59(26-28-69-43-22-17-37(18-23-43)49(65)48-44-24-21-41(62)30-46(44)71-51(48)39-15-19-40(61)20-16-39)25-9-8-10-27-68-32-47(64)58-52(55(4
L-838417 Catalog No.:M13786-2 Discovery of the First PotentL 838417 is a selective partial agonist at the 2, 3 and 5 subtypes of the GABAA receptor and an antagonist at the 1, with binding Ki values of 0. 79 nM, 0. 67 nM, 1. 67 nM, 267 nM, 2. 25 nM and 2183 nM for 132, 232, 332, 432, 532 and 632. Product information CAS Number: 286456 42 6 Molecular Weight: 399. 40 Formula: C19H19F2N7O Chemical Name: 5 ({[7 tert butyl 3 (2,5 difluorophenyl) [1,2,4]triazolo[4,3 b]pyridazin 6 yl]oxy}methyl) 1 methyl 1H 1,2,4
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