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3-d]pyrimidin-4-yl}-3-chloro-2-methylbenzene-1-sulfonamide
and cell proliferation
InChi: InChI=1S/C27H26ClF3N6O3/c1-3-39-25(38)20(32)12-16-4-6-17(7-5-16)21-14-23(35-26(33)34-21)40-24(27(29
InChiKey: AUMDBEHGJRZSOO-UHFFFAOYSA-N
SNS-314 mesylate Size:Solid 2 mg 3-d]pyrimidin-4-yl}-3-chloro-2-methylbenzene-1-sulfonamideSNS 314 is a synthetic small molecule Aurora kinase (AK) inhibitor with potential antineoplastic activity. Aurora kinase inhibitor SNS 314 selectively binds to and inhibits AKs A and B, which may result in the inhibition of cellular division and proliferation in tumor cells that overexpress AKs. AKs are serine threonine kinases that play essential roles in mitotic checkpoint control during mitosis. Product information CAS Number: 1146618 41 8
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