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PubMed Central PMCID: PMC3632326
MI-2 was used at 10-25 µM concentration in vitro and in the cellular assays
InChiKey: JRVXFGNCHKHBPA-UHFFFAOYSA-N
Smiles: CCNC(=O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2C=CC=CC=2)[C@H](O)C[C@@H]1O
ASTX-029 Size:10mg solid PubMed Central PMCID: PMC3632326ASTX 029 is an orally bioavailable inhibitor of the extracellular signal regulated kinases (ERK) 1 and 2, with potential antineoplastic activity. ASTX 029 inhibits ERK dependent tumor cell proliferation and survival. Product information CAS Number: 2095719 92 7 Molecular Weight: 584. 04 Formula: C29H31ClFN5O5 Chemical Name: (R) 2 (6 (5 chloro 2 ((tetrahydro 2H pyran 4 yl)amino)pyrimidin 4 yl) 1 oxoisoindolin 2 yl) N ((S) 1 (3 fluoro 5 methoxyphenyl) 2
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