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AN-2728 - CAS# 906673-24-3 Catalog No.:M10493-2 In the panel of 42

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Description

In the panel of 42 human tumour cell lines

Epivir HBV

Debio-1452

Formula: C12H14N4O2S

AN-2728 - CAS# 906673-24-3 Catalog No.:M10493-2 In the panel of 42Crisaborole, also known as AN 2728, is a topically administered, boron containing, anti inflammatory compound that inhibits PDE4 activity and thereby suppresses the release of TNFalpha, IL 12, IL 23 and other cytokines. At the time of publication, three phase Ib clinical trials, a IIa trial and a IIb trial of AN 2728 in patients with psoriasis had been completed; the compound was also undergoing phase II development for atopic dermatitis, but no data

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