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CH-0793076 Catalog No.:M33332-C reduces DNA damage and down-regulates

SKU: 11112877388

4.7
USD100.00 USD137.00

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Description

reduces DNA damage and down-regulates the ratio of Bax/Bcl-2 in bone marrow cells exposed to radiation

Solubility: H2O : ≥ 50 mg/mL (88

m-PEG6-Amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs

Smiles: NC(=S)C1=CC(=CC=C1)C1=CN(C2CCN(CC2)S(=O)(=O)C(F)(F)F)C2=CC(CNC(=O)C3CNC3)=CC=C12

CH-0793076 Catalog No.:M33332-C reduces DNA damage and down-regulatesCH 0793076 (TP3076), a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH 0793076 inhibits DNA topoisomerase I with an IC50 of 2. 3 M. CH 0793076 is efficacious against cells expressing BCRP (breast cancer resistance protein). Product information CAS Number: 534605 78 2 Molecular Weight: 458. 51 Formula: C26H26N4O4 Chemical Name: (10S) 10 ethyl 10 hydroxy 23 pentyl 8 oxa 4,15,21,23 tetraazahexacyclo[14. 7. 1. 0,. 0,. 0,.

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