Pay in 4 interest-free payments of $7.25 Learn more
Ships within 48 hours · Estimated delivery Aug 10 - Aug 15
InChi: InChI=1S/C27H21N5/c1-3-9-21(10-4-1)22-16-14-20(15-17-22)19-29-27-25(23-11-5-2-6-12-23)31-32-26(30-27)24-13-7-8-18-28-24/h1-18H
and inhibits the growth of two xenografted tumors in mice in vivo
Chemical Name: 2-(4-(2-hydroxyethoxy)-3
despite the fact that (S)-2-HG more potently inhibits enzymes previously linked to the pathogenesis of IDH mutant tumors
CID-2011756 - CAS# 638156-11-3 und Library of Histone Demethylase InChi: InChI=1S/C27H21N5/c1-3-9-21(10-4-1)22-16-14-20(15-17-22)19-29-27-25(23-11-5-2-6-12-23)31-32-26(30-27)24-13-7-8-18-28-24/h1-18HCID 2011756, CAS No. 638156 11 3, is a cell active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester induced endogenous PKD1 activation in LNCaP prostate cancer cells. IC50 Value: 100. 7 uM (cellular inhibition of phospho Ser916 PKD1 activity) [1] Target: PKD CID 2011756, has pan PKD inhibitory effects (PKD2 IC50 = 0. 60. 1 uM; PKD3 IC50 = 0. 70. 2 uM) with similar, albeit not identical, potencies which may be expected for an ATP
US$ 65.00
US$ 4395.00
US$ 197.50
US$ 52.80
US$ 9375.00