AM095 (free acid) - CAS# 1228690-36-5 tate) and disrupts the repair of

and disrupts the repair of dsDNA breaks probably through suppression of Rad51

inhibiting growth

TG101348 induces apoptosis in both HEL and Ba/F3 JAK2V617F cells

and triggers mitochondrial dysfunction in MCs

AM095 (free acid) - CAS# 1228690-36-5 tate) and disrupts the repair ofAM095 is a potent LPA1 receptor antagonist because it inhibited GTPS binding to Chinese hamster ovary (CHO) cell membranes overexpressing recombinant human or mouse LPA1 with IC50 values of 0. 98 and 0. 73 M, respectively, and exhibited no LPA1 agonism. Lysophosphatidic acid (LPA) is a bioactive phospholipid that signals through a family of at least six G protein coupled receptors designated LPA1 6. LPA type 1 receptor (LPA1) exhibits widespread